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Genetics Test 3

 

Genetics  
Test 1   Test 1a*
Test 2   Test 3
Quiz 1   Quiz 2
Quiz 3   Test 4

*including answer

 

PART A: MULTIPLE CHOICE

 

1 .   Which if the following are found in DNA?

 

     a .   ribose, phosphate, A, T, G, C

     b .   ribose, phosphate, A, T, G, C, U

     c .   deoxyribose, phosphate, A, T, G, C

     d .   deoxyribose, phosphate, A, T, G, U

     e .   none of the above.

 

2 .    Which if the following are found in DNA?

     a .   deoxyribose, phosphate, A, T, G, U

     b .   ribose, phosphate, A, T, G, C, U

     c .   ribose, phosphate, A, T, G, C

     d .   deoxyribose, phosphate, A, T, G, C

     e .   none of the above.

  

3 .    An allele is:

     a .   a gene

     b .   a trait

     c .   a form of a gene

     d .   a form of a trait

     e .   a slippery animal served in ethnic restaurants

 

4 .    Which molecules are used in translation?

     a .   tRNA, mRNA, endonuclease

     b .   tRNA, mRNA, DNA, ribosomes

     c .   ligase, mRNA, DNA, ribosomes

     d .   tRNA, RNA polymerase, DNA, ribosomes 

 

5 .    A certain population contains 20% A, 50% B of the ABO alleles.  What would the percentage of O allele be?

     a .   0%

     b .   1%

     c .   9%

     d .   10%

     e .   30%

 

6 .    A certain population contains 20% A, 50% B of the ABO alleles.  What would the percentage of O blood type be?

     a .   0%

     b .   1%

     c .   9%

     d .   10%

     e .   30%

 

7 .    How many (alleles) are there for eye colour?

     a .   1

     b .   2

     c .   3

     d .   more than 3

8 .    Which phage was studied when overlapping genes were discovered?

     a .   φX174

     b .   T4

     c .   pBR322

     d .   T2

     e .   RNE

 

9 .    Introns are:

     a .   areas of RNA which are expressed

     b .   areas of RNA which are not expressed

     c .   areas of DNA which are expressed

     d .   areas of DNA which are not expressed

 

 

10 .   Histones are:

     a .   found attached to DNA

     b .   used to wrap DNA

     c .   both of the above

 

 

11 .   Translation is:

     a .   conversion of mRNA to polypeptides

     b .   reading of mRNA to make polypeptides

     c .   conversion of DNA to RNA

     d .   reading of DNA to make mRNA

 

  12 .   Transcription is:

     a .   conversion of DNA to RNA

     b .   reading of DNA to make mRNA

     c .   conversion of mRNA to polypeptides

     d .   reading of mRNA to make polypeptides

  

13 .   The least important codon is the:

     a .   first - regardless of whether it's A,T,G or C

     b .   second - regardless of whether it's A,T,G or C

     c .   third - regardless of whether it's A,T,G or C

     d .   T - always

     e .   U - always

 

 

  

 

               PART B:  SHORT ANSWER

1 .    State the differences between the structure of DNA and RNA. 

  

2 .   How many different base sequences could arise from a gene fragment 20 base pairs in length?

 

  3 .   Phenylketonuria involves a single mutation of amino acid number 138 - a switch from alanine to proline.  What was (or were) the original codon(s), and what is the mutated codon(s) likely?

 

 

4 .   Show the polypeptide for the gene fragment -AUGGACCGUUGAAUU-.

  

 

5 .   Using the fragment -AUGGACCGUUGAAUU-, do a mutation which would result in premature termination of the peptide.

 


PART C: ANSWERS YOU CAN PROUD OF (hopefully)

1 .   A certain recessive trait exhibits Mendellian dominant-recessive characteristics.  One in 100 exhibit the trait. 

     a .   Show the Punnet square using the ratios (proportions) of the two alleles.

 

     b .   In Canada, (popl 27 000 000) how many carriers are there?

 

  2 .    Describe the process of DNA replication.  Include the  concept of 5'3', DNA polymerase, ligase, unwindase, and Okazaki fragments.  Use diagrams.

 

 

3 .   The mitochondrial genome of Saccharomyces Cerevisae (yeast) contains 84,000 base pairs.  It makes 9 proteins.  There are only two initiation sites reading left to right, and only one initiation site reading right to left.  What strategy is being employed?

   

4 .   A phage makes proteins which requires 450 bases each.  It makes 6 different proteins.  What can you say about the genome?

 

  5 .   A gene sequence is:

     -----CGUAAUGCCAAAAGGUAAGUAA----

 

     a .   How many polypeptides could this gene "theoretically" make?  Explain.

 

 

6 .    Describe the process of recombinant DNA.  Use the example of cloning the human oxytocin gene.